my sole concern is creating too much stress on cables, any cable, especially where wire has a junction with plugs or connectors. my other pet peeve is separating cable runs as much as possible, so that when i have to change something, i am not pulling on 3 other cables along with the one i am removing.
If there is a company that sells flexible (yet sturdy) wires that sound really good, that would be a huge advantage over what i have now.
concerns over RF, etc. would seem 2ndary when there is no way to get these stiff, uncomprimising interconnects and PC's to stay out of the path of all of the OTHER interconnects and PC's.