That’s where Patapoutian and his colleagues came in. After pinpointing cells that responded to changes in pressure, they identified 72 potential genes that might encode an ion channel receptor to facilitate that sensitivity. Of those genes, they found just one — the last candidate they tested — that did so. It coded for a novel ion channel protein, Piezo1, that could be activated by mechanical force.This is probably an explanation for frisson, which lots of us experience when sound waves physically touch us and not with just our ears.
All the best,
Nonoise