Not necessarily. Look at Musical Fidelity M8xi. That is a fully balanced unit which is a true dual mono amp and even has separate power supplies for the two side of the amp and the XLRs are paired right next to each other. It's a design choice like anything else.
If it is unbalanced, sound quality will be dictated by the quality of transformer used to convert the signal unless your system is noisy or you have ground issues. If it is an unbalanced amp, odds are the RCAs will sound better than the XLRs. Especially if it is tube based gear.
If it is unbalanced, sound quality will be dictated by the quality of transformer used to convert the signal unless your system is noisy or you have ground issues. If it is an unbalanced amp, odds are the RCAs will sound better than the XLRs. Especially if it is tube based gear.