I have upgraded with Audioquest panther. I was expecting an improcement but was shocked at the level of detail and dynamics. well worth the cost.
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Yes, I have Signal Cable. Works fine. I can't tell how big an improvement it made as I purchased it for my Stadium 11 which didn't come with a cable. My Stadium 111 which I bought later came with a standard cable but I never had a listening panel to compare them. Trying to change the cable while running back and forth trying to listen did not seem likely to tell you much. I eventually replaced the stock cable on the 3 with one made by an individual that advertises on Audiogon. Happy with that one also. As I run both at once any comparisons involve rebalancing my system so I haven't done it but my impression is that either is a definite step up from the standard cable.
For years I have wondered how upgrading the stock Rel for my B3 to anything else would make much of a difference and just 3 weeks ago I got my answer. I bought a Nordost baseline sub cable with the neurtrik and spades for a high level input. All I can say is the amount of information I hear is tremendous. All low notes sound so much more natural. I think because of the speed silver brings, the time alignment together is so much better. I had no idea what I was missing (neither could my dealer).
Sorry I can't comment on Signal Cable but I would think any upgraded cable should be an improvement.
I'm contributing to an old post, but I hope I can still help someone. I have the 13ft Signal Cable with speakon for my Rel T2. There is an obvious improvement compared to the stock cable. The bass is tighter and defined. I tried the comparison many times and the Signal Cable actually gives bass the authority it deserves. I was not a believer in cable improvement but after hearing the difference with Signal Cable, I was converted.
If you can swing the scratch, I highly recommend the Synergistic Research Tesla REL SPEC Reference active high level cable. Nothing, and I mean nothing can beat this cable for a downright panoramic soundstage and deep, pitch articulate bass combined with what seems like another half octave of bass extension. It also makes the blend between the REL and your main speakers absolutely seemless.
As an aside, the power cord one uses on the REL's also makes a very profound difference and the SR Tesla T3 active power cable is a very good match which solidifies the attributes of the Tesla REL SPEC Reference high level cable or another high level cable one choses to implement.
Just get rid of the stock REL high level cable...