Heater Current (Crucial): A 12AX7 draws 150 mA (at 12.6V) or 300 mA (at 6.3V). The 12AD7 draws 225 mA (at 12.6V) or 450 mA (at 6.3V). Do not use a 12AD7 if your amplifier uses a series-heater string (often found in certain vintage hi-fi gear), as the higher draw could overload or damage your power transformer.
They are swappable, but certain parameters need to be checked.
I would REALLY advise sending EAT an email to be sure.

