Do Fuses make a difference ib sound?

One way of playing with fuse results is used (as I mentioned earlier), but also the QSA black. At $28-30, could be a fun experiment. Start with your pre or amp. I think I heard a difference… but who knows. I then moved to the used SR orange for all my main components and put the QSA in my Aurender, adding one for my sub. All in I have $270 invested in 6 fuses, a relatively low amount. 
Gemini recommendation: 

Because the QSA Black sits at the bottom of their line, it is a relatively low-risk experiment compared to their upper-tier colored fuses, which scale into thousands of dollars.

If your digital front end, source components, or amplification are highly optimized and you enjoy fine-tuning the final fractions of a percent of system performance, it is a fun trial to see if your ears detect a change in the noise floor. However, if you are looking for a massive, undeniable shift in tonal balance or power, investing that money toward room treatment, speaker positioning, or clean power delivery at the wall will always yield a more predictable, measurable return.

Audio magic thier top fuses I find $300 each a bit pricy ,but after 175 hours a more natural presentation and like them better then the $600 synergistic fuses overall 

Alfred gives you 30 days to audition for a full refund .

Nope. Next question.

My dealer convinced me to try the synergistic research purple fuses in my Rogue Audio. This difference was not subtle. I felt like I had a new upgraded amp. Sound opened up. No idea how it works but maybe it’s akin to upgrading your tubes. Now I have em in my preamp and phono. Like previous folks said, give em a try. 

As with many others on the thread that actually tried them, yes I tried SR fuses with the option to return for a refund and I kept them.  Subtle but noticeable.  YMMV