That's a big room. I own the Arendal 1528 Tower 8 10th anniversary editions and can attest to their ability to fill a big space but they aren't for everyone. You need a LOT of power, 450-1000 watts for full range and the are BIG/HEAVY/LARGE. As someone else already suggested, you have to go listen to whatever you're shopping. (Arendal gives you 60 days in home trial but shipping is difficult cause they're LARGE but it's free.) One key here is if you don't like them when you first hear them, you never will. Don't let anyone talk you into "breaking them in". I'm not saying that's not a thing, but be careful of having someone talk you into something you don't like.
After that, I'd shop: Goldenear T66, Perlisten R7t, MoFi Sourcepoint 888 or V10, KEF R11 w/subs, Perlisten R5t w/subs. That's for new. Used is a totally different recommendation. Used, I'd be shopping Perlisten S7t, KEF Reference 1 or 3 Metas, (w/sub), Paradigm Persona 9H. Careful of open baffles, electrostats, or horn speakers. They often have placement restrictions and most aren't for everyone.
p.s. a quick search on soundstage network and their loudspeaker measurement page will give you some areas to shop. It won't replace you listening to these for yourself, but can help quickly identify types of preferences using the frequency response graphs. https://www.soundstagenetwork.com/index.php?option=com_content&view=article&id=16&Itemid=140
Good luck! Can't wait to read what you went with!