Yes, work great, yes.
Take a look at the AM Acoustics Room mode simulator. It will help you see the mode you have trouble with, place your speakers and listening location outside of it but also help you decide how to place your bass traps. If the mode is across the top and bottom of the wall, vertical bass traps won’t be as useful.
Also, while a combination of room acoustics + EQ is the recommended solution you can clip strong bass nodes with a parametric EQ like miniDSP alone. It isn’t a full solution as it wont’ solve nulls, or smooth the bass response across the room but clipping strong room modes is 80% of the way there, and may let you raise your subwoofer level up so it’s fully balanced with hte rest.
The same is often true in reverse. bass traps can really help, but the severity of the room mode may need assistance from EQ.
I can tell you that the anti-EQ crowd is dead wrong when it comes to sub/bass integration. Going from a badly performing room to one that has perfectly integrated bass with EQ and traps is glorious. Don't be a purist.

