What type of speaker would sound better?

The idea is to match the amp/pre with the speakers. You might be wasting 245 watts of amplifier on speakers that really would sound good with 25 watts or less. 

I had a 30 watt class A amp that far out performed a 200 watt mono blocks especially the bass.

A good idea to decide your listening position.  I would not think in terms of "filling " the room. You don't want a PA system.  Micro details and dynamics are special if you can get there. 

I've heard some 2 way speakers that sounded better than everything else in the same line from the same manufacturer! Power, room, placement all play a part, but unless you're just looking for loudness usually the 2 way with better components ought to win.

3 way 2 way allways have a midrange hole 
what would sound best is the 3 way of the vintage allison AL130 w/ the unique proprietary and inovative  sealed cabinet dual 8" push pull woofers and the CONVEX cones of the tweeter and midrange  nothing since is as inovative and amazing 50+ years old tech not surpassed 
Roy Allison was amazing ! 

My all allison 11.2 HT  is pure sweetness ! total envelopment ! has taken a bit of time to find all the speakers!  

2 way allways have a midrange hole 

Not the case.  Some speakers with a very large woofer mated to a tweeter that doesn’t play low perhaps, but most 5-8" woofers can mate seamlessly with many tweeters.  Their downside would be tend to be limited of deep bass output, not a midrange hole.

@gdaddy1 

+1 I have used your automotive manufacturing analogy many times to debunk the need for a Speaker to cost $100K+ (or $50K for that matter!!). Speakers just aren’t that complex and science on good sound is pretty much decided outside of driver technology and exotic cabinet materials. None of which cost anywhere near as much to design and manufacture as an automobile, even a crappy car! 
 

To the OP’s question, do a deep dive into either the 2 way or the 3 way and see how the thing is built. What separates a good speaker from a great speaker is the driver technology (think ScanSpeak, SB Acoustics Satori, Purifi), and cabinet construction. Cabinet bracing is SOOOO important and the brands that cheap out on it are putting one over on you (Klipsch, Tekton, Zu Audio, etc.). People like to talk down about B&W and Wilson because the voicing is a little hot, but their cabinet technology and drives are top notch! If the 2 way has better drivers and cabinet than the 3 way, it has a strong chance of sounding better.