Focal sopra 2/Gryphon Diablo 300 not good match

I had the exact same system you have.  Diablo 300 with N10 and Sopra 3s.   I did find it to be a bit edgy and intense with certain music but not like you are describing.   I had wireworld eclipse 7 and never used silver cables.   
I have EVO Scala’s with Octave gear now and absolutely love it.

I agree with others you may want to try tubes or class A amps.   Maybe change up the DAC as well.

While I am not sure that I agree with d2girls that we necessarily want to strive for a flat sound signature, I do think he/she makes an excellent recommendation that you may want to buy an eq.  In fact, the Schitt Loki is only $150 and users here give excellent reviews noting no degradation in sound from the unit.

D2girls; my confidence 30 and 50 measure very flat; Dynaudio designed these in their mega expensive Jupiter Lab; they are like a precision instrument that does not emphasize any particular frequency, so I’ll have to disagree with you; Some speakers are just voiced one way or another with actual program material however; Trust me; if the recording is live and well balanced the Dyns will portray that about as perfectly as possible. There is no roll off in the tweeter; 
I would be willing to bet most folks prefer a sound that emotionally connects them to the music, which by definition is the embodiment of emotion; our ears are not microphones and our brains are not oscilloscopes; I think Nelson Pass said that and I happen to agree; Cheers all and enjoy the music!!

I had a similar experience with some lesser Focals (profile 918) a few years ago. I picked them in a shop demo room over everything else I heard that day and I’d even taken my own amp and CD player in for the demo. Got the Focals home on loan for a week and just couldn’t get them to sound anything less than excruciating in my room. I ended up with Thiel CS1.6 so it wasn’t too much detail that was the problem. I‘ve head other Focals since at shows, mostly with Naim amps (which I use), including some large Utopia models and never found them enjoyable despite the merger/takeover which presumably means Naim amps will be among those used for voicing the recent models.