Difference in sound between copper and silver digital cables?

Given the different way in which analog signals and digital signals are transmitted down connections (optical speaker cables, anyone?), it seems 100% commonsensical that design is going to play a large part in any perceived difference, and that carrying over to digital conventional associations of copper vs. silver in analog situations is spurious.

I have built and sold USB cables for years trying all manner of conductors. Easy to hear the sonic character of pure silver vs. pure copper conductors in identical designs. One can also easily hear synthetic vs natural conductor coverings. My customers could easily tell when sending them two different USB cables to try and report back. Same general differences as found in analog cables. Materials have a sound regardless of design. They just do.

Is it possible some are less able to hear these differences? Yes indeed.

@audiozenology, perhaps if you speak from empirical evidence doing comparison on your own and say you perceive no difference, then your comment may lend some credibility but just stating theory from science book or wherever makes you fall into the same bucket of cynics.