I can share some generalized thoughts based on my experiences owning the Hermes and the Singxer SU-6 (currently), and with streaming Tidal, Qobuz, and stored files using Roon in my system:
- Assuming the server is powerful enough to competently process Roon Core, I have not heard any sonic differences between servers.
- Streamers (aka. Roon endpoints) have resulted in a more significant impact on the sound of my systems.
- A DDC provides isolation, reclocking, and format conversion (e.g., multiple outputs), but since a competent DAC also provides isolation, so the better the streamer and DAC, the less influence a DDC should have on the sound of an audio system to the point where the user may not "hear" a recognizable difference in the sound of their system when using a DDC.
- One benefit a DDC does provide is that, in converting the streamer’s digital output format so that multiple formats can be selected, the DAC’s optimal digital input format may be used.
- I2S may work fine with some components but, in general, is over-rated as a connection protocol between two audio components and is not likely to significantly change the overall sonic presentation of most DACs compared to an optimized S/PDIF or USB connection (IME).

