Thanks everyone for your most valuable inputs!
I will take the loudspeaker-first approach. I will audition speakers that will work best in my environment and that I want for the long-term at the most I can afford. I am already quite enamored with DyanAudio, PMC, and Sonus Faber. Maybe KEF.
I will then select amplification with the idea that finding what works best in the short term with the idea that I will upgrade in the future. Class D? Class A/B. I dunno - not knowing is what makes the adventure so grand, right?

