Many machines can mount and spin 12"10" 7" lps,; some slots on the tops are size specific regarding size and quantity, Kirmuss makes a poing of not having more than 3 in order to keep them spaced so the bubbles can get between them.
if you mean the chemicals safe/effective for materials78’s are made from, I suggest you ask others, including Kirmuss, and
member lnitm, OP of this related discussion:
https://forum.audiogon.com/discussions/kirmuss-ultrasonic-vinyl-cleaner
if you ’search discussions’ (search box top of window), you will get many like this
https://forum.audiogon.com/discussions/how-best-to-clean-old-78s?highlight=clean%2B78s

