Depends on how much it's been used. A light use subwoofer on a 2ch audio system -versus- a subwoofer constantly hammered in a dual purpose audio system and home theater setup (combined use) is a used subwoofer I'd avoid unless you are a fan of the cabinet, get it for low cost, and don't mind rebuilding it later.
Having helped multiple friends replace the woofers and amplifiers in factory made subwoofers and there is no guarantee a high grade sub will last longer than a low cost one. Seen and helped fix some nice subs that did not last long and then the factory parts were no longer available so it was a total cut / fab / do over.
Can also be rewarding to build your own subwoofer kit with a new amp, new woofer. If the amp or woofer goes bad later, it's easier to fix since you already know it having built it.

