How can a system be judged with highly processed, non acoustic music?

I basically know what an instrument or human voice sounds like. I understand that almost all recordings, analog or digital, go through some level of processing. I also know that there are many, many recordings which strive to present a natural, real sound. To me, I can best judge a system playing lightly or non processed acoustic music.
This is also my preference for listening in general. And for me, it is vinyl.