The midi range, not the tweeter, is the most important driver in a speaker.

Andy the W19/Graphene has a super low sensitivty, 85db,,so the W22 will have same,,,= rules out any dream ofa  845 amp. 
Thats the trade off, I miss out on the 845's dreamy liquid mesmerizing mids in chamber/light classical (= 845 can not reproduce complex orchestra),,but the SEAS W22 + Seas T25002 offers its own magical sound world. 
and can handle both complex thick classical and obviously light classical/chamber.
+ The SEAS T25 voices the human voice like no other tweet I've heard, as it isa  true rare Midtweet has that NEO magnet system. 
I see your Nextel 5.5, has HEX magnet, good, but not Neo magnet system, 
The Neo magnet allow the amp superior power, as the super powerful Neo magnet draws the currect of electrons/=The Siemens,  at a  much quicker pace = less resistance to the amp = cleaner sound. 

I have nothing against the Magnesium Seas line, but I have to be a fanboy and plug the Scanspeak Revelators which is what I use. Warm, and in the right (i.e. large!) cabinet, have amazing bass for the size. If you are doing a 2-way I highly recommend them. :)
Of course, this is a hobby and fun so pick what you like, I just reserve the right to be a fanboy from time to time. :)

Yes the Scan Rev looks likeav  awesome bass response,,But I am not into heavy bass. 
I need midarnge as all my muisc is classical, no bass guitar, no heavy drums. 
= as per OP, Midrange is the most important fq's in any speaker. 
SEAS wins out big time. 
sure the SEAS are 2x's the price of Sacn.s , but if we are going to buy $$$$$$$$$$ amps, why not speand a  few extra bucks and get the most critical compoenet of our systems. 
I've heard $100K Jadis systems on a  YT vid at a  LV show,, sounded like crap, ,,why?
Speakers were 100% crapo. 
Go figure.  
I hope folks realize, big is not always better. Some folks tend to think wow, look at the huge speakers here,,,they MUST BE GREAT SOUNDING,,,haha, Graets ound can come froma  2 way and bow out speakers with 20 drivers. 
I've heard this way back in 1974, The big Macintosh had 25 drivers in each cabinet,,,The interphase A1's  witha  passive radiator woofer +  woofer, anda  tweet<<<< blew the $$$$$$$$$ Macintosh out the water>>>
Go figure. . 

I never said the Scanspeaks lacked in midrange. They are wonderful. I only meant to say they also had big deep bass in the right cabinet. Never said they were chest thumpers either.


The integration of a speaker with the room is so critically important and why a good 2-way can outperform a lot of other speakers. Smaller = less problems in the lower octaves.


But ... speakers with built in room correction in the lower octave can perform even better. :)