I have compared(owned) many cables in my system.
I have gone from the VD 'Audition' cable to the 'Signature' and now use Nite I latest before the II.
I find it very good in dynamics and realism not found in any other pc. The best I have come across. That being said the David is supposed to be much better which I have not heard.
The Audience pc was kinda dull in my system.
Now I have a similar situation as Brian.
I have Audience AU24 ic's and speaker wire but the pc's don't have the same sound. I would have expected them to have similar characteristics.
I have used,JPS Labs,PS Audio,Blue Circle,Shunyata,Cardas Golden Ref./Cross,Synergistic Research,TG Audio although the TG was the best of the rest.
Oh,I also am using a Audio Magic "Illusion" on the power amp which is a great match, at least so far.
All trial and error this pc game.