Help with fatiguing sound in my PC system


I replaced my Halo Pre and Denon changer with a PS Audio DL III. I run lossless music into it from iTunes on a PC (Windows 7 64bit, core i7, 16MB RAM), I use a Pangea USB cable into a MF V-link, then go into the DAC with a Wireworld ultraviolet coax. The increased detail, clarity, resolution and extension are remarkable, but so is the amount of listening fatigue. The highs are too much, but the music sounds muffled if I add the pre-amp back. My system is profiled in the link below. I have some ideas, let the voting begin:
1 - buy an offramp or a pacecar (can't afford it!)
2 - use better USB/coax/interconnects/speaker cable
3 - apply acoustic treatments to the room
4 - use a software player (Jplay) that sits on top of iTunes
5 - buy speakers with different tweeters (Quad 22L2/Focal 826v, this is happening, but not any time soon)
6 - get a better amp (McCormack/Odyssey, distant future)
7 - tweak Windows 7/iTunes settings (WASAPI exclusive mode?!?)
8 - adjust speaker position/toe in (already did this and it helped a little)
I am thinking about trying #3/#7 next. Ideas? Thnx in advance.
realremo
I went from Monitor Audio (Silver 8's if I remember correctly) to Quad 22l2's. The quad soft dome tweeters helped some, but the the speakesr still had a mid band dip that excentuated the highs so I sold them too. Speakers matter as much as anything but there's a number of ways to tackle a resolving/fatiguing setup (ways that usually cost $).

I just swapped out a new battery for my old macbook, even that switch has caused a high frequency push that is unbearable for now (hopefully the battery breaks in....things sound better with the crapped out battery in the macbook, whether it's plugged in or not).
I use a Mac Mini for my computer audio so not sure how well this applies. I am however, using the PS Audio DLIII which I don't find fatiguing in my setup. Not going to offer advice but will tell you what I did to get sound that rivals my cdp.
First off I rip files to AIFF using XLD for bit perfect copies. I tried Apple lossless as well as AIFF with itunes with error correction but none of these were quite good enough. When I used my pc I ripped AIFF with EAC (exact audio copy) to get bit perfect rips. It takes a bit longer to rip but it's worth it IMO.
Next, I decided on the optical out after comparing it to the USB. I don't believe USB is ready if you want the best sound. Even with the optical out I wasn't satisfied until I inserted a Monarchy Audio DIP and then fed the PS Audio via the coax input. I may remove the DIP and compare now that I have everything else sorted out.
That's where I'm at. Perfect rips, no USB out and the DIP. I feel no need to change anything at this point. The only problem for me is 90% of my files were ripped before I started using XLD. My task is to get another external hard drive and rerip everything with XLD. Hope this helps a little.
Fatigueing sound is generally due to high jitter at the wrong frequencies. This will not get fixed without fixing the source or interface with the Master Clock in it.

Most people feel that they can use a $200 interface with a $2K DAC. The opposite is more optimum. Use a $2K interface with a $200 DAC. This interface is more important than the DAC.

Steve N.
Empirical Audio