You're considering two very different animals.
If I'm understanding Dynaudio Sub6 spec "(Hz @ 85dB +/- 3dB): 16" as well as the manuals suggestion of placing the unit at the listening position to excite your rooms unique standing wave bass modes to position the Sub in, ie: the subwoofer crawl, the Sub6 is a true -3dB@16Hz subwoofer. Aside from this more detailed room integration the Sub6 appears to offer an application for far greater seamless speaker integration. In my experience with a big REL you ain't heard nothin' yet.
All REL products are merely Sub-Bass Systems (woofers) with a dramatic -6dB roll off that simply does not play loud enough to excite a rooms standing bass waves. This allows them to be placed most anywhere in the room. If your not concerned with hearing the delicate (not boomy) extra low frequency presentation found on most recordings and do not want to be bothered with locating your rooms standing wave modes then the Classic should do just fine, minus the Sub6's full presentation.
Your amplifier manufacturer is the ultimate authority on grounding resolution not REL.
Your Freya has three sets of outputs. If the Sub6 position is a long distance away from the Freya you have the option to use inexpensive custom length XLR or single ended cables from Blue Jeans or Monoprice Cables.
All the best with your search.

