There is nothing that explicitly says you can't use a full tube integrated with those speakers but you are right to be cautious. one of my worst demos (as a consumer years ago) was with a popular tube integrated and the 805 d3s.
The VAC 170i which is 85w into 4 ohm taps would be an interesting choice in the full tube range. The min impedance on the 805 D4s is 4.6ohms. This is not brutal for any amp with 4 ohm or 6 ohm taps.
The Octave V 80 SE with a black box or super black box and KT88 tubes would be pretty awesome here and do a lovely job. You can add KT120 or KT150s for more power but I think it sounds better with KT88s. This is an OTL and does not behave like a normal tube amp.
The Riviera Levante is one of the best integrated amps I have ever heard if you can live with its 30w into class A. The AB setting is not as amazing sounding as the pure Class A.
The Unison Unico 150 would be a good choice. it is their flagship integrated and is quite musical. It certainly will have the grip to handle the B&Ws.
McIntosh and B&W get paired regularly for a reason. They are really good together and I would never discourage anyone from that combo.
Pathos would also be worth looking at. They make some really good sounding amps. I don't know exact models from them.
Full disclosure, I am a VAC, Riviera and Unison dealer. I have no association with the other brands.