I think it is safest to say a Cartridge left alone is a safe Cartridge.
A Cartridge put into service is exposed to a set of required procedures, that from a slight user misjudgement or user error, is quite easily incurring a damage.
A Cartridge used and in need of achieving good fettle or to be fettled with, becomes the Cartridge that is at highest risk of incurring a damage. There is no solid sound advice to be offered, but Good Luck.
If you don't know, you don't know and the individuals not knowing is the usually a cause of the damage when being reported on.

