I was not a "cable denier," but I was a bit skeptical of spending "lots" of money on cables. I did figure that buying reputable cables in the lower mid-range would make a difference in the sound. I did spend on better speaker cables, however, including AQ Rocket 88, some custom Mogami's, and Raven Audio; they made some improvement, but nothing dramatic. Then, I read a number of items about Silversmith Fidelium speaker cables and, learning that the owner, Jeffrey, offered a trial period, I gave them a go. Well, both my non-audiophile (but music loving) wife and I were shocked when we hooked up the Fidelium speaker cables to the Odyssey Kismet (in Khartago cases) mono bloc amplifiers. The improvement in sound quality--tonal character of instruments, sound stage, and the location of instruments and voices--was simply astounding. I knew within a minute or two that the Fidelity's far surpassed anything else I had tried thus far.
I then purchased a pair of Fidelium XLR interconnects to connect my Gungnir2 DAC to my Rogue Audio RP-7 preamp--replacing mid-grade Morrow interconnects, and while the improvement was nearly so dramatic, it was quite noticeable. I also am using Ice Age Audio OFC power cords in my system. While my system is probably mid-fi, I am quite pleased with the results.
So, for me, the best way to buy cables is to find a company that offers a trial period and go that route; so far, there is nothing that I have had to send back.