I also noticed that the higher the sample rate the more processing power is required. By a fair amount. Supposedly this creates more noise. To be honest, I couldn't hear any benifit of up-sampling so I just backed away from it.
Depends what you are doing with it, but sure if you are upsampling and doing parametric EQ then that will take more CPU time. It does seem to affect the heat generated by a DAC though. That is, higher sampling rates seem to create more heat and sometimes more stability issues. Another reason I avoid anything higher than 192k.

