system synergy

So, the basic question is: how important is synergy between amps and preamps? In particular, how much benefit can be expected from mating amps with preamps that are in the same series? One would think that a good signal from a preamp is a good signal from a preamp, but I imagine impedance and maybe bandwidth matching might be very important. I'm not gear-head enough to say.

There is likely no general answer to this, but I do have a specific case in mind.

I have an Accuphase P-300 and an CJ Motif CR8 Pre (solid state). Both of course excellent vintage (and vintage-ish) units. But the Accuphase was designed with the C-200 preamp in mind, as it were, and the CJ Motif with the CJ Motif power amps in mind.

So, what would I likely find if I switched the Motif for a (sound) C-200 (features aside)? And likewise, what woud I find if I switched the P-300 out for a Motif Power amp (assuming proper matching with loudspeakers)?

Any experienced answers, or even educated speculations appreciated.

Thanks.