Soooo, what are your oppinions about what listener fatigue is and why it's caused?
I feel listening fatigue is a mental and/or emotional sense of being, not so much a physical issue with the ears. I find it most commonly occurs with me when my system has taken a turn towards a more resolving, clinical, analytical type of sound. Detail, detail everywhere, mental stimulation overload leads me towards shorter and shorter listening sessions. Sometimes leading me to not firing up the rig at all. The mind is burning up trying to take in all of this information and detail.
The cure is to remove the gear, cables, etc. that led to this hyper-detail sound in the first place and replace them with more musical pieces.