SET’s are max’ish 25wch most are in the 2-8wch range so not really practical for your KEF’s 85db sensitivity.
SET one tube amplifying the whole sine wave. usually 2-8-25wpc
SET Parallel same as above but two or more tubes in parallel so they both do the full sine wave just added together to get double ’ish the power as the SET.
Push Pull you can get much more power. these run two or more tubes each pair splits the sine wave in half one amplifying the plus side the other the negative side of the sine wave hence the push pull (very general as there is other configurations but you get the idea). its when you put the plus and negative together is where you get the distortion.
If your thinking tubes (I love tubes myself) you will need a push pull amp for sure. your KEF’s are 85db sensitivity so more then the SET 25wch probably closer to 100wpc min.
i’m sure others will have run the KEF’s on tube amps and will give some suggestions for amps and what power ranges work for them. If your replacing the KEF's as well then your whole world of tubes amps opens up
remember the lower the power the more efficient your speakers will have to be. if your going to dip into the lower then 25wch SET world (more realistically 8 wpc for the 300b for example) you will need to look for speakers that are 94-95db min the higher the better here. anything below 90db and your really looking at push pull amps anything below 2wpc (45tube is an example) and your in the 100db and up efficiency area.
Oh SET they are so wonderful but harder to find a speaker but worth the effort IMO. SET are very seductive in the midrange but can if not done well be rolled off a bit at the highest top and lowest bottom. they are very musical.
Parallel sounds the same as the SET just more power, well more as in a parallel 300b amp gives you 16wpc lol.
Push Pulls can give you same power as SS so no issues but more power is more money and more tubes to replace. Push Pull amps are big and dynamic sounding but don't have as a seductive midrange as the SET. They do extend further in the bottom and top though and generally have better bass (that's a bit price dependant).
I've had SET and PP and like them both, if you want a more intimate, seductive musical experience go SET if you want a bigger louder, slightly more detailed and better bass control (price dependant) sound then PP.