I don't think 2-way is better than 3-way, or vice versa. I do think that if you sit six feet from the speakers 3-way won't work - not enough distance for the drivers to focus at the sitting position. Without the proper driver integration, you will loose a balanced, seamless transition across the frequency spectrum. 3-ways certaintly have their place, many, but not in this situation, IMHO.
3 way vs. 2 way
I currently have Mirage M5si bi polar speakers, I believe these have two tweeters and two 6inch drivers. For my room size I want to go to a conventional speaker. I would also like to give a high end store in my area the business as the owner is a friend. He carries Totem and B&W. I notice may of the Totems have only a tweeter and a driver. Can I get as good sound out of smoething like that as compared to a speaker with 3 or 4 in the cabinet?