OP: Roon’s DSP capabilities are REALLY good, but what they won’t do is help you with the sub to speaker integration. If your speakers are ported, plug them, then use the DSP to carefully integrate the sub to the mains and let it deal with peaks. If you also use bass traps you can also weaken nulls.
So, I am really now bringing up two separate issues. One is how well the sub integrates with the room, and the other is with the main speakers. A separate DSP for the sub (or a multi-way DSP) let's you finesse that. Roon can only apply global EQ to try to hammer down what's broken elsewhere.
Having said all that, you may not have any issues which this solves, so if you have good measurement software, you may be able to do a very good job using just the sub's settings (like LP filter Hz) and Roon.

