I live in the mostly mid-tier cable world from Audioquest. I inherited a half-meter pair of high-end (more than a $1,000) RCA cables. I use these between my preamp and amp. Since all the other cables are not close in quality, I don't think the priceya Kimbers do much.
I have no doubt that if I could afford to buy high end in almost any well-known cable brand (when I look at them in comparison, they all seem to use the same basic materials and techniques) my system would sound better. But $20,000 plus on cables is not going to happen.
Just one note on whether an expense (that you can afford) is worth it. When we A/B cables or anything else, we listen very closely for minute differences we then exagerate in our minds. My bottom-line is this: Would I know the difference if I left the house for half an hour and came back to my stereo. Would I notice if one streamer (for example) was playing instead of a more expensive one.
When I bought my Moon 280D streamer, I could not tell the difference in a five-minute test between it and much more expensive streamers. If the sales guy prompted me to listen to the cymbal decay or whatever, I might have noticed. But I don't think I would have noticed at home, even when I was listening to a piece with both my conscious and unconscious minds. In other words, not worth the extra $6K.

