I have followed your posts, but remind me what you are using for software/UI, and if you have any kind of server.
I guess my last post might have been a bit confusing. The DAC combined with an endpoint streamer has worked well for me and is a significant improvement over SPDIF/USB in my system, I recommend it. But I have a server that runs Roon core separate from the networked DAC, which only runs the Roon endpoint software. @audphile1 does something similar with a Roon Nucleus (I think). I think there are non-Roon configurations (JPlay maybe?) that would allow you to have no server, but someone else would have to chime in on how that is done and whether it works well.
As for which DAC, I have not heard the Weiss, but from what I read it sounds fairly detailed. The Meitner is known to be warmer and might be a shift for you. I "think" that Bricasti and the Tambaqui might be closer. But if you really like the Weiss sound, but just want an upgrade, the 501 is a good choice. It's all up to taste and synergy at that point.