Looking for an Amp or Integrated Amp with a solid midrange presence

That’s not a weak amp (??), my daughter has one in her rig. That Yamaha should have had no problems with your speaker. In fact, you would be hard pressed to find something else better for under a 1000 bucks. What exactly did "weak" mean?

Do you have something else wrong with your speaker or anything else in the chain, electrical, etc? I mean you killed 2 amps recently and apparently the Yamaha felt real weak.

I suppose you could raise your budget to 2000 bucks and knock yourself out with a meatheaded Schiit Wotan. If the Wotan also felt "weak", you have other problems.

https://www.schiit.com/products/wotan

 I tried the Yamaha AS801 but it was much weaker than the 100WPC implied.  My listening room is 14’ wide by 16" deep.  Used for movies and 2 channel stereo only , no home theater .  Budget maximum would be $1500 range.

No electrical issues, had all the plugs re-wired and my NAD 316 is running fine.

Class D Audio GaN amps will fill the bill well within your budget. 
I’ve become quite impressed with what I hear out of mine. 
They also have a try’em out period. 

If you could find a used Krell 300i, that would definitely give you what you looking for. A Hegal 390 would also fit the bill. An electrocompaniet ECI 6 MKII also would fit the bill. I own all 3 of these integrated and can attest to their sound signature

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I would go with integrated with remote control

I looked around, then went over your budget, found this Krell

https://www.usaudiomart.com/details/650252303-krell-s-550-integrated-amp-2-channel-black/

I never saw or heard this model, this review popped up

https://www.absolutesounds.com/pdf/main/press/2013_07_Krell_S550i_HFN.pdf