Vandersteen Quatro CT or Wilson Sabrina

Both speakers are top quality offerings!  I'm a 30+ year Vandy owner and love the truth of that sound.  However, as @stereo5 said, you should probably audition them again.  They represent very different approaches to sound reproduction.  Which one puts a smile on your face and gets your toes tapping?

For your sake, don't let yourself feel rushed to make a decision.  IMHO there is no more important system decision.  Good Luck!

+1 stereo5 and tomic601  stereo5 your quote "That Kind of up front Wilson sound is great at first, but over time would irritate the Hell out of me." is what I was tempted to say but then there are many listeners who like that more "upfront" perspective".  For me, in my limited experience listening through Wilsons, they do wear on you the longer you listen.  Vandersteen's offerings have that plane of the speakers and behind soundscape that invites you into listen.

Tomic's comment about the powered and equalized bass from the Quatros is a great selling point!

Best of luck making the choice that is right for you.

@tomic601 I have two 2wq subs. in my system and my family used to complain about how they could "feel" the bass upstairs (I am in a dedicated basement room). After looking into the idea of decoupling my Treo CTs and loving the results (clarity, openness) I ordered giant decouplers from Herbie’s for the subs. Wow! The decouplers raised the bottom firing subs. about 1/2 inch off the carpet, yielding what my ears perceived as a cleaner bass response. The most astonishing result was I can play Donald Fagan’s "Morph the Cat" at volume, go upstairs and not experience the bass at all, and that album has kick-butt bass. Huge deal. If you take the leap into sub-land maybe that would be a good solution for your living concerns.

Here’s hopin’!!