I think it may be something very simple like how you are doing the the bias adjustment. Especially if (you didn't say) the 45 minute "blow time" is unrelated to listening levels. In other words, something besides the driving voltage is causing the tubes to begin drawing too much power after warm-up. (I could be wrong, but.....)
You should adjust the bias with the speakers connected, but the inputs disconnected, and only after the amp has been running for 20 minutes or so. If you don't do it this way, you may be inadvertantly setting the bias too high. Also, the bias for 6550's and KI88's is generally somewhere around 35-45 ma, Does the manual specify 150? I understand what Newbee says about 150ma for the quads, but I had two sets of quad 6550's in each of my ARC monoblocks, and only biased each set of quads to 32ma!
If re-biasing doesn't solve the problem, it could be a bad tube. You could replace the one tube without much loss in performance. A matched pair is better, but matched quads are really overkill.
If you think it is the tube, and/or the bias suggestions aren't relevant, I'd recommend getting a matched pair, and saving the one good one from the previous pair for a spare.
You should adjust the bias with the speakers connected, but the inputs disconnected, and only after the amp has been running for 20 minutes or so. If you don't do it this way, you may be inadvertantly setting the bias too high. Also, the bias for 6550's and KI88's is generally somewhere around 35-45 ma, Does the manual specify 150? I understand what Newbee says about 150ma for the quads, but I had two sets of quad 6550's in each of my ARC monoblocks, and only biased each set of quads to 32ma!
If re-biasing doesn't solve the problem, it could be a bad tube. You could replace the one tube without much loss in performance. A matched pair is better, but matched quads are really overkill.
If you think it is the tube, and/or the bias suggestions aren't relevant, I'd recommend getting a matched pair, and saving the one good one from the previous pair for a spare.