^Yes!
Headphones eliminate room interactions, but are perceived very differently than speakers or unamplified live performances. Even the rare binaural recordings, though a vast improvement in this regard, don't completely remove this unnatural listening experience. Some processors can help, but I have yet to hear any approach that sounds completely natural. Headphones can be a useful tool to better analyze specific attributes, certainly have their place in certain circumstances, but IME as a holistic listening experience they ultimately fail.
Headphones eliminate room interactions, but are perceived very differently than speakers or unamplified live performances. Even the rare binaural recordings, though a vast improvement in this regard, don't completely remove this unnatural listening experience. Some processors can help, but I have yet to hear any approach that sounds completely natural. Headphones can be a useful tool to better analyze specific attributes, certainly have their place in certain circumstances, but IME as a holistic listening experience they ultimately fail.