I have a HT system built around my Vandersteen 3A Signatures, and have a few observations that may have some value for you.
First, as Mg123 said above, don't expect the 2Ci's to produce extreme sound pressure levels. They will do movie track and LFE sound fairly realistically -- but their strength is in accurate sound reproduction, which makes dialogue and nuances in the soundtrack very realistic.
If you are going to buy the 2Wq sub rather than the V2W (which is intended for HT use), you will need a pair of 2Wq's to properly do HT sound. The 2Wq is about 6db less efficient than the V2W, and they were intended to be used as a stereo pair to supplement each main speaker. Hence, it takes a pair of 2Wq's to get the same sound pressure level at a given voltage compared to the V2W. Also, the V2W connects directly to the pre/pro's ".1" / LFE outputs, whereas the 2Wq is driven off the full-range audio signal.
I have a pair of 2Wq's in my system, and think they are terrific. However, about 90% of the time I use my system for pure audio, so the HT aspect is obviously less important to me. They do a very good, but not sensational, job of re-creating explosions, etc., but they are GREAT with the music in soundtracks.
I have a VCC-1 Signature center channel, and think it does an adequate job. (My listening room is rather narrow, so there is not a lot of distance between the left/right main speakers and the VCC-1. If you have a lot of room between your 2Ce's and the proposed center channel, you may want to consider a different center speaker.)
The VCC-1 center channel speaker is not Vandersteen's best product, however, and if you have a large room, then you should investigate the VCC-5, which is a much larger center channel speaker. Of course, it has a MSRP of $2000, so it's a significant investment. Also, don't feel tempted to buy the Vandersteen VCC-1 Signature. I first owned the regular VCC-1, and had it upgraded to the "Signature" model, and subsequently regretted spending the extra money -- not worth it.
Regarding the rear surrounds: don't cheap out on this. If you do, I guarantee you will regret your decision. The reason I caution you about getting decent rear surround speakers is that the Vandersteens have excellent resolution, so poor rear surrounds become very noticeable. This does not mean you have to spend a fortune on the rear surrounds, but you ought to be considering a pair that has a MSRP of $1000-1200. I tried several different speakers for rear channel surrounds, including two brands of direct-radiating speakers: a pair of B&W DM 601's, and a pair of Coincident Technology Triumph Signatures. I finally settled on the M&K SS-150 THX tripole surrounds (MSRP $1200), and have been very pleased with them.
The standard advice for surround speakers is to buy the same brand as your main speakers. This is reasonable advice, but you can still get excellent results with other brands that mate well with your 2Ce's. The Vandersteen VSM's are very good, but they are somewhat large and may prove to be "not wife friendly".
There have been a number of recent threads about "which amp should I buy for HT use", and "2-channel + 3-channel vs. 5-channel". I suggest you look at the Audiogon archives to see what has already been discussed. (To get my 2cents in here, I have a Bryston 4B-ST amp for the main speakers, and a Bryston 5B-ST for the center/rear speakers, and I am VERY
pleased with this setup. I also use a Bryston SP-1 pre/pro, but there are a number of very good pre/pros on the market today to choose from.)
Best regards - Scott C