I much preferred the Twenty Five to the DR-25 in my system. I think the old Stereophile review of the Fifteen compared to the DR-15 also applies to the 25 series.
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I own a DR15, bought it brand new. I keep it turned on 24/7, never dissapoints, sounds sensational, and is as close to bulletproof as you can find. I have driven some strangely loaded speakers and the amp didn't even sweat.
I would not worry about any single pair speaker load, I would start thinking about just "enjoying the music".