Of course your room and desired listening levels will be paramount in this regard. I think the answer to your question is yes, but more power would be better. The difference between 40 and 50 watts is minimal. As a rule of thumb (not carved in stone by any means) there is a kernel of truth to the old saying "double the manufacturers minmum suggested power". I believe that the Vandy 2c's minimum suggested power was 40 Watts.
40 watt tube integrated enough for vandy 2's?
does the jolida 202 have enough power to match the low sensitivity of the 2ce's? Does the fact that it is a tube amp give it somewhat of an upper hand when it comes to it's numerical shortcommings in terms of power? I want tube, but don't want to spend more than 600-700 (for used). Is the 303 (50wpc...i think) a better way to go?