Having a Space that is 2-3 times longer than wide would help with one possibility.
Speaker selection / recommendation might prove difficult.
An example would be: Two Way vs Three Way Designs.
MBL 126 omnis should give you an idea of what is possible.
I would suggest listening.
Demos / Shows
Find a sound in a playback system that has a / the desired quality.
Already you have some reference with CM10 S2.
Start with a component that you like!
The current Book shelve Speakers may serve well for some experimentation.