Dedicated 10 gauge NM-B lines twisted or straight

y, sounds like you should sub-panel. It might even be cheaper that way:

• Cost of 480 ft of AWG 8: 480 × $1.00 = $480
• Cost of 160 ft of AWG 6: 160 × $1.50 = $240

Just reviewing data from the internet:

To minimize loss, aim for a voltage drop under 3% for sensitive equipment. 

The voltage drop calculator, says that 10 gauge wire over 100 feet should only cause a drop of 1.6V (1.33%) at 16 amps.  However, Google says that the drop would be 5.4V (4.5%) at 20 amps.

The same voltage drop calculator also says that 6 gauge wire over 100 feet should cause a drop of 2.37V (2.0%) at 60 amps.  Here Google says that the drop would be 4.7V (3.9%) at 60 amps, which is what I would need for a sub panel.  

So, perhaps just go with the easier option, and run 3 x 10 gauge wires.

Listen to Erik,  I’ve been an electrician for a long time,  his points about voltage drop are sub panel are valid

rich

...y, but imagine sitting there with your 10AWG wiring, wondering "how much better would it sound with 6AWG?" 

It turns out that the voltage drops are nearly identical for 10 gauge at 120V vs. 6 gauge at 240V.  In my previous calculations, the 6 gauge was calculated at 120V, not 240V.  A 4 gauge wire might be a little better, but I haven’t run the calculations on that.