Koegz, in a nutshell, that is the whole point of balanced line operation. The system was created to eliminate interconnect cable problems.
There is a standard that has to be conformed to in order for this to be true. If the conformance is not there, you will still hear differences in the cable.
The primary hanging point with most high end gear is the 600 ohm termination standard. What this means is that the equipment should be able to drive a load of 600 ohms (which might be at the input of the amplifier) without difficulty (for example loss of bass). For tubes this usually means an output transformer, or very large coupling caps, 100uf or more. Most high end manufacturers don't want to put in such a large capacitor at the output of the preamp, as it will color the sound and for the same reason aren't usually too keen about an output transformer either. That's why conformance to the standard is rare.
There is a standard that has to be conformed to in order for this to be true. If the conformance is not there, you will still hear differences in the cable.
The primary hanging point with most high end gear is the 600 ohm termination standard. What this means is that the equipment should be able to drive a load of 600 ohms (which might be at the input of the amplifier) without difficulty (for example loss of bass). For tubes this usually means an output transformer, or very large coupling caps, 100uf or more. Most high end manufacturers don't want to put in such a large capacitor at the output of the preamp, as it will color the sound and for the same reason aren't usually too keen about an output transformer either. That's why conformance to the standard is rare.