Thanks everyone. It's cool to read everyone's take on the question.
I don't know how to answer the question for myself - yet, at least. The reason I'd be interested in having a second setup is that I love the idea of having setups optimized for different sonic signatures, but don't really want to deal with resetting vta, vtf, etc. every time I change cartridges.
As I've thought about it off and on throughout the day, and read others' responses, I've honed in on a couple questions I need to answer for myself: do I really need a mono cart (same situation here @dogberry) and/or do I want both a suspended and non-suspended table for variety? I've only ever lived with non-suspended tables and am curious about suspended tables, lately.
In any case, I fully agree on the importance of a good phono stage. I'd be inclined to go with a single phono stage with multiple inputs, and get variety from table/tonearm/cartridge combos.
@noromance, I checked out your system. Great solution for vinyl storage! I'm getting too old to crawl around on the floor trying to read spines.