I have not tried them, but since I'm flying to Italy in two weeks I started doing research about the problem of noise on airplanes. At Headroom.com they don't recommend noise canceling headphones even though they sell them, they recommend Etymotic Research ER-4 earphones, since they provide 23db of isolation as well as the flatest feq response of any headphone!! I just bought a pair (arrived in two days). They sound great. They take a little getting used to and are expensive ($269 from Headroom, $330 list).
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