The room being an office I assume room treatment is out. Our collective experience tells us that there is nothing less fatiguing than a well balanced sound with minimal room interference and phase anomalies.
Decent speakers properly aligned (with advanced room correction) to the room will likely sound better that great speaker in a room full of issues. The quality of components does matter but they won't compensate for room issues.
Decent speakers properly aligned (with advanced room correction) to the room will likely sound better that great speaker in a room full of issues. The quality of components does matter but they won't compensate for room issues.