Cause of Muddled Middle?

Thanks for all of the responses. I do need to improve the room as it has too many naked hard surfaces. I've also considered electrostatic speakers. I auditioned a set of Martin Logan ESLs that had very nice separation although I didn't have any of my own music with me at the time.

I also considered upgrading my cables to Clear Day Shotgun or Double Shotgun cables. These are both solid silver conductors.