Correct me if I am wrong but people seem to confuse spikes, noise and thunder. Thunder or excessive spikes are easy to control as they are usually adressed by devices in parallel with the line so they short when a high voltage hits MOV and gas tubes are usualy used. I haven't heard any comments on isolation transformers these can decouple your gear from the line which is a huge benefit (any comments?) as far as the 220V/110 comment goes this is usually a diode acting as a Voltage divider not really a benefit in my opinion.