Start over--HiFi rig ---clean slate

I'm interested in the thoughts of this forum.
All seem to be well read and informed.

IF YOU WERE TO START OVER:

Cost would be a variable and you were to pick the pinnacle of your desires,(& hopefully listened to them) what would it be: Speakers,amp,preamp & source

The format:
1) speaker brand and name
2) amp
3) preamp
4) source

My wish:
1) Thiel cs3.7
Add two velodyne DD-15 subs
2) Devaliet 400 mono-2 ( not listened to)
3) above
4) computer audio- mac with amarra symphony & Dirac IRC

Jeff