2x2x12inch or 2x15inch subwoofers


I am deciding between either a Rythmik G22, E22, or E15HP2.

I will buy 2 of each.  Would 2 12inch drivers deliver more room pressureization or 1 15inch driver?  Salk recommends 1 15 inch over 2 12inch woofers.  I have 2 REL S510s in the front of the room connected by both High Level and .1 and the speakers higher up would be in the back of the room.

Room is 2200 cubic feet, and has full accoustic treatments.
dmaddox77
"... The idea that small speakers are faster is a myth that needs to die.."

A Velodyne rep once asked me; 12 inch or 18 inch, which speaker gets there quicker?...I said; They both get there at the same time or they are in distortion.   
Four 10" will be better than any of those. Deeper flatter faster more powerful more articulate. Not even close. Do a search for Swarm, Distributed Bass Array, DBA, etc. The Audiokinesis Swarm Subwoofer system just won an award for best component. See the recent thread and all of us who know just how important it is to have MORE subs and not bigger subs.
For home theater, get as many and as big and powerful of subs as you can afford and have room for, assuming you're not living in an apartment. As far as how deep they'll go, look at the specs. I love and own Rythmik subs, but for sheer output, I'd take a look at power sound audio also. You'll get better information on a home theater forum than you will here. 
My room is 17x24x9.   https://systems.audiogon.com/systems/8367 The focus is music but we watch a lot of movies. The other night we were watching Oblivion and there was a point where they shot Tom Cruise and he fell and there was this bwoommmmm and I don't know how low or what frequency all I know is I felt the earth move. The whole room was shaking. And this is with Podiums, and Pods under all the subs. Absolutely phenomenal bass. Super powerful, incredibly clean, almost like you could see the pressure waves with your eyes. Honestly had no idea the damn thing could even do that!   

I just do not see any dichotomy between music and home theater systems. I do see people following HT dictates and that never turns out well. Follow the very best high end sound solutions, get a DBA, you will see.
I don't know if this helps or not, but I have a pair of the E15HP2's (4000 cubic room w/ full acoustic treatment).
If I'm watching a movie with my wife I can use both subs (main system volume is lower than watching a movie myself).
If I'm watching a movie alone, and she's upstairs on either the main floor or the 2nd story floor, I have to turn one of them off, and the volume down on the other. It's amazing how much these things can pressurize a room.
I thought about a pair of G22's, but didn't like where the plate amp is situated.
Best of luck going forward whatever your decision is.