preamp vs amp: relative effect on sound?


Recently, there was an interesting thread on combining a tube preamp with a SS amp, which is what apparently a lot of people do.

So two questions.

Q1: in a preamp + amp combo, does each unit affect the eventual sound equally, 50/50, or is one going to affect the sound more than the other?

Q2: in a combo of higher gain preamp + lower gain amp, will more gain being provided by the preamp have any effect on your answer to Q1?
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The preamp is further up the signal path and therefore has a greater influence. So, while the right answer is always it depends because it is a system and components are different. But say maybe 65 / 35 pre / amp for thinking about it. But if you have an underpowered amp then upgrading this will have a disproportionate difference, as an example.

Q2.. All the components I have bought have not varied enough that it has influences Q1. In most cases the gain on the preamp normally been roughly the same as I swapped them. I remember some big differences in the  40 to 50 years ago timeframe.