I'm selling speakers for the first time and concerned about fraud

Zero feedback dudes just pray a lot!!

Take your payment via postal money order. Thieves avoid using these as the gov't takes fraud seriously. Or take personal checks but wait until they cleared the purchaser's bank. Many of the complaints revolve around the recourse that buyers have when PayPal is used and they know it and sleeze ball members, feedback notwithstanding, take advantage of it. 

Good luck!

In addition to Newbee's excellent advice:

First, Google the person’s screen name, and see what turns up. Second, ascertain the person’s real name and location, and check it out on Google, Facebook, Linkedin, Intelius, etc.

You may be surprised at how much information can be found out about people online.

Good luck. Regards,
-- Al

So PayPal's fraud prevention stuff isn't really a safeguard? I'm just worried he'll get the package and claim something's wrong with it or something weird. I don't do this often so I'm aware I'm basically fresh meat.

So PayPal's fraud prevention stuff isn't really a safeguard?

Sadly, no.

PayPal offers much more assurance to the buyer than it does to sellers.
Too many horror stories to even get started.

As a long time seller/buyer, I don't think that I would accept an offer from a buyer with zero feedback on a pair of speakers, requiring the use of PayPal AND shipping.

I would be either looking for a cash 'n carry local deal, or a USPS money order, bank, or even personal check (wait to clear before shipping) if I was going to ship.

Granted, as a buyer with no feedback, I would be leery of buying from a seller with no feedback without using PayPal.
Just remember that PayPal may help the buyer out, particularly if he uses a credit card, but PayPal is not there to protect the seller.

Good luck with your sale.
John